|Research Center for Bioinformatics and Biosciences|
The ReCBB is composed of two research sections: Genome Informatics Group, Molecular Function Analysis Group and Environmental Genomics Group..
► The mission of this center is to elucidate the genome organization and function of commercially important aquatic organisms, such as bluefin tuna. By using next-generation DNA sequencing platforms, several analyses are performed, including sequencing of whole genomes, comprehensive analysis of expressed genes, and bioinformatic gene prediction. Structural analysis of genomes facilitates the development of DNA markers for promotion of fisheries resource management and conservation. Functional analysis of genomes provides means to identify and characterize genes involved in high-rate growth, disease resistance, and high-temperature tolerance, which could benefit aquaculture.
► The center also performs metagenomic analysis of marine microflora. High-throughout sequencing of marine metagenomes is useful for characterizing species diversity of marine microflora and developing novel biological techniques to monitor the marine environment.
► Researchers are also responsible for on-site inspections of suspected aquatic living modified organisms (LMOs) under the “Law Concerning the Conservation and Sustainable Use of Biological Diversity through Regulations on the Use of LMOs ” and developing molecular genetic techniques for detection of LMOs. Inspections are performed in a specially equipped testing facility for LMOs.
next-generation DNA sequencers.
|Genetically modified medaka and zebrafish showing fluorescent color (a) and PCR detection of the inserted gene (arrow) (b).|